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March 17, 2009 |
Volume
17, Number 3
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Microchip Biotech’s
Spring Arrival Adds to Park's Biotech
Contingent
Company Joins Roche Molecular Diagnostics,
Waters Corp. in Hacienda
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MBI’s
new Stoneridge Drive facility.
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By Nicole Zaro Stahl
NETWORK Editor
Is there a biotech cluster emerging in Hacienda? Barney Saunders,
Ph.D. and Chief Commercial Officer at Microchip Biotechnologies Inc.
(MBI), suggests as much, noting the recent arrival of Waters Corp. and
Roche Molecular Diagnostics’ new research facility. Now Microchip
Biotech is following in their footsteps, with refurbishing underway in
the 16,000 square feet of space at 5720 Stoneridge Drive the company
will occupy later this spring.
Like its fellow Hacienda
life-sciences tenants, MBI’s specialty is tools for biotechnology
research. Where one such company puts down roots, others are apt to
follow, Saunders observes. “The more companies in the tools space that
establish themselves here, the more attractive it becomes to others.
Plus Hacienda is a great location, and we have a very nice-looking
facility that will be built out the way we want it,” he says.
MBI’s
focus is on streamlining sample preparation and analysis for the life
sciences, through both equipment and sample size. The company’s
proprietary technology dramatically shrinks the need for large sample
volumes to nanoscale size, reduces labor costs through automation,
increases reliability, and can provide major savings in the use of
highly expensive reagents and scarce samples.
Until now,
Saunders explains, the processes for preparing biological samples have
tended to be complex and expensive, with researchers having to choose
between two less-than-perfect alternatives: error-prone manual
procedures or expensive, large robotic systems. MBI’s vision is “to
create devices—using simple valves, routers, and circuits in glass and
plastic—that integrate, automate, and simplify the analysis of
biological materials.” The cornerstone of this approach is
microfluidics, a miniaturized environment where sample quantities are
smaller than a water droplet. The company’s exclusive microscale
on-chip valves (MOVe) technology offers superior sample mixing
properties, a major leap forward in automating and integrating
sequencing reactions, making the entire process much more efficient.
MBI’s
first product, the Apollo 100, is specifically designed for
Sanger-based DNA sequencing, the standard at the thousands of
university DNA-sequencing centers around the country. The company’s
ultimate goal is to develop complete “sample-to-answer” solutions in a
portable footprint, thus allowing all kinds of analysis and measurement
to take place outside the lab. “This will lead to the creation of
simple-to-use, fully automated, high-performance systems with reduced
reagent costs and improved analytic efficiencies using only the tiniest
amounts of sample,” Saunders explains. Among the potential applications
he mentions is the ability to carry out DNA testing at a crime scene.
Other examples include testing agricultural crops for pathogens like E.
coli O157:H7, which contaminated fresh spinach in 2006, while they are
still out in the field; and helping hospitals detect microorganisms
that produce problematic infections like methicillin-resistant
Staphylococcus aureus.
Incorporated in July 2003, MBI has
grown to approximately 40 employees. The new facility will include wet
research labs, a small clean room for prototyping, and small-scale
manufacturing rooms, “very different from a full-scale fab,” Saunders
points out. “In classic Silicon Valley mode, we contract out for
various pieces, and then do the final assembly and test
here.”
For more information, visit
www.microchipbiotech.com.
OOBA’s Hibiscus
Beverage Packs Plenty of Flower
Power
After Exclusive Distribution Deal with Whole
Foods, Drink's Distribution to be Expanded to Other Chains

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With
the introduction of three new flavors this month, OOBA now comes in six
varieties.
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By Nicole Zaro Stahl
NETWORK Editor
“Something special is happening here,” remarks Janet Di Giovanna,
Chief Marketing Officer at HiBix Corp., which moved into new
headquarters at 5860 W. Las Positas Blvd. in early January.
Di
Giovanna is referring to the track record of the less-than-a-year-old
company whose product has been singled out as “one of the top 10 trends
to watch in 2009” by Datamonitor, an international market research
firm.
HiBix is the maker of OOBA, the first-ever line of
sparkling beverages based on hibiscus extract. The first two OOBA
products, Hibiscus & Lime and Hibiscus & Orange,
debuted in
16-ounce bottles in the grab-and-go coolers at Whole Foods markets this
past fall.
Formula creator and company founder John-David
Enright has a great story to tell about how that transpired. Familiar
with the healthful attributes of hibiscus from his years in the
pharmaceutical industry, Enright set about developing a new kind of
“good-for-you” beverage from scratch in rented lab space in Hayward. He
also established some important business contacts. Then, last July, he
walked into a meeting with Whole Foods corporate buyers in Austin
carrying a refilled soda bottle with a lab label on it that read,
“Hibiscus with Attitude.” After a taste test, the buyers liked the
“gently carbonated, lightly sweetened” beverage so much they decided on
the spot to do an exclusive national roll-out.
As Enright
suspected, the all-natural OOBA drinks proved to be an ideal fit for
the label- and ingredient-conscious Whole Foods shoppers, a highly
educated, discerning, and adventurous demographic that “understands
‘better-for-you’ products better than anyone in the United States,” he
says. A 55-cents-off hang tag on the distinctive PET bottle (the shape
of an inverted ice cream cone) invited consumers to try the next new
thing.
“We shipped product to every Whole Foods store in the
nation, almost 300 of them,” comments Di Giovanna.“We will have run
close to 700,000 bottles of OOBA, which is pretty meaningful in the
grand scheme of things, especially considering that, with the exception
of a few food shows aimed at distributors and a small couponing effort,
we have done no advertising or major promotions.”
The
next step is already underway, with HiBix expanding distribution to
other major grocery chains. Enright may have labored by himself in the
lab, but he assembled a seasoned sales and marketing team and
contracted with “a very well-established organization in Los Angeles”
to produce and bottle OOBA.
The almost-overnight success has
not ruffled Enright’s aplomb. He finds tremendous gratification in
sharing the healthful properties of the hibiscus at the heart of OOBA,
an acronym for One of Botany’s Advantages. “The science
behind
the efficacy of the hibiscus species is solid,” he states. “Hibiscus
extract contains many of the same antioxidant compounds as red wine,
including flavonoids, polyphenols, and anthocyanins, which have been
demonstrated to prevent the oxidation of LDL or ‘bad’cholesterol, and
positively affect hypertension (high blood pressure).”
So eat, drink, and be healthy! For more information, visit www.oobabeverage.com.
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