This month Royal Philips, a global leader in health technology, announced the expanded commercial availability of LumiGuide 3D Device Guidance across Europe and the United States beginning in January 2026. LumiGuide is the world’s first real-time AI-enabled light-based 3D navigation solution for image-guided therapy. It represents a breakthrough in radiation-free navigation, allowing physicians to visualize and guide devices inside the body using light instead of continuous X-ray. The upcoming wider commercial rollout marks the next step in Philips’ long-term commitment to improving radiation safety and dose reduction in image-guided therapy, according to officials.

The LumiGuide navigation system has FDA clearance and CE marking. It seamlessly integrates with Azurion, Philips’ proven, world-leading image-guided therapy platform designed to drive procedural innovation across clinical domains. Focused on improving outcomes, efficiency, and safety, LumiGuide joins a growing suite of intelligent, AI-enabled supportive and therapeutic devices integrated on the Azurion platform–a portfolio that spans both guidance technologies and therapeutic tools–redefining how clinicians plan, guide, and perform complex procedures with greater precision and confidence.

Powered by Philips Fiber Optic RealShape technology, LumiGuide, is the first solution to use light to visualize the shape and position of LumiGuide wires and compatible endovascular catheters inside the body in real time and in 3D–without X-ray. By reflecting light along an optical fiber integrated into the guidewire, LumiGuide shows high-resolution, full-color images from any angle, giving physicians instant orientation during complex endovascular procedures. LumiGuide uses AI to quickly and accurately align any image with the patient's anatomy. This technology allows clinicians to navigate with precision, while significantly reducing radiation exposure for both patients and clinical staff. Using this advanced technology, complex cases such as aortic repair procedures can be performed 37% faster and with up to 56% reduction in dose area product, a measure of radiation exposure associated with imaging procedures.

“Moving LumiGuide from limited to full commercial availability is an important milestone in expanding access to advanced image-guided therapy,” according to Stacey Beske, Business Leader Image-Guided Therapy Devices at Philips.

“By bringing this light-based navigation technology to more hospitals, we’re helping clinicians treat complex vascular disease with precision and safety, while reducing radiation risk for patients and teams in the lab,” adds Atul Gupta, M.D., Chief Medical Officer of Diagnosis and Treatment at Philips, which became a Hacienda in 2017.

LumiGuide is the latest innovation built on Philips leadership in Image Guided Therapy and the proven Azurion platform – the foundation for procedural innovation across clinical domains. LumiGuide demonstrates how Philips continues to advance minimally invasive therapies through integration of intelligent systems and devices that combine real-time insight, precision navigation, and procedural efficiency. Built on a platform that treats over 6.4 million patients each year across more than 80 countries, with high-quality, low-dose imaging and enhanced workflow efficiency, LumiGuide extends Philips’ commitment to making image-guided therapy safer, faster, and more effective for patients and clinical teams.

Over the past years, LumiGuide has been used in more than 2,000 clinical procedures, integrated with Philips Azurion image-guided therapy platform. Building on this experience, Philips continues to invest in clinical evidence generation to help clinicians optimize the use of LumiGuide in everyday practice. LumiGuide builds on Philips’ broader portfolio of innovations aimed at reducing or eliminating radiation exposure during image-guided procedures.

For more information about Royal Philips, please visit www.usa.philips.com/a-w/about.

For more information about LumiGuide, please visit www.usa.philips.com/healthcare/clp/aw/lumiguide-image-guided-therapy.